In this webinar, Rachel Tham, Principal Statistician at Veramed, and Thomas Kumke, SSI RWE Strategy Lead at UCB, will explore certain tools for pragmatic trials and their application before jumping into Cluster Randomized Trials, considerations to keep in mind, and their benefits with a unique ability to naturally account for herd immunity in vaccine studies.
Agenda
- Defining pragmatic trials and their role in evidence generation
- Tools and applications for pragmatic trials
- Common challenges of pragmatic trials and their operational and statistical solutions
- Key considerations you might need to be aware of BEFORE being “pragmatic”
- The important differences between randomized control trials (RCT) and cluster randomized trials (CRT)
- The application of cluster randomized trials in vaccines as an example of cluster randomized trials.
- Key considerations for statisticians when conducting a cluster randomized trial
