Biometrics Built Better

Arm Wrestling with Uncertainty: Meta-Analysis for Survival Estimation

Strengthen clinical trial design with meta-analysis for survival estimation. Learn how biometrics and biostatistics improve Phase 3 success and reduce trial risk.

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When there’s no clear standard of care, there’s no room for guesswork. Accurate survival estimation becomes critical to getting Phase 3 trial design right first time.

In this conference poster, Isabelle Smith, Manager, Statistics, explores how meta-analysis in clinical trials can be used to strengthen survival estimates while accounting for variability across studies.

By applying robust biostatistics and biometrics approaches, including random-effects meta-analysis and scenario planning, teams can:

  • Improve sample size calculations
  • Better account for heterogeneity and uncertainty
  • Reduce the risk of underpowered Phase 3 trials
  • Support more confident, data-driven clinical development decisions

With the right statistical expertise and scalable biometrics support, biotech and pharma teams can move beyond simplified assumptions and design trials that stand up to real-world complexity right from day one.

Click on the poster below to learn how biometrics and biostatistics improve Phase 3 success and reduce trial risk.

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